If we believe that our greatest good is that God might exalt us, make us happy without him, and affirm our innate goodness then we will be sorely disturbed when everything in creation and in the mission of God cries out the opposite.
God's mission is to be known among the nations not to make much of us. Creation testifies to this. The sun, the moon, and the stars do not cry out to testify of our greatness--they proclaim the majesty of God. Everything but our own hearts testifies to the greatness of God. If we think it's about us then life will deeply disappoint us.